At a glance
All gamesHead-to-head4 recent
349ers wins
1Bills wins
Oct 7, 2012 · Week 5
Buffalo Bills3 - 45FINALSan Francisco 49ers Nov 30, 2008 · Week 13
San Francisco 49ers10 - 3FINALBuffalo Bills Dec 26, 2004 · Week 16
Buffalo Bills41 - 7FINALSan Francisco 49ers Dec 2, 2001 · Week 12
Buffalo Bills0 - 35FINALSan Francisco 49ers
FormLast five before this game
49ersWLLLL
Arizona Cardinals33 - 21FINALSan Francisco 49ersDallas Cowboys24 - 17FINALSan Francisco 49ersSan Francisco 49ers18 - 37FINALSeattle SeahawksSan Francisco 49ers27 - 46FINALCarolina PanthersLos Angeles Rams0 - 28FINALSan Francisco 49ers BillsLLWWW
Buffalo Bills30 - 19FINALLos Angeles RamsBuffalo Bills16 - 0FINALNew England PatriotsArizona Cardinals18 - 33FINALBuffalo BillsNew York Jets37 - 31FINALBuffalo BillsBuffalo Bills7 - 13FINALBaltimore Ravens
Also in Week 62016 season
Thu, Oct 13
Denver Broncos13 - 21FINALSan Diego Chargers Sun, Oct 16
Jacksonville Jaguars17 - 16FINALChicago Bears Los Angeles Rams28 - 31FINALDetroit Lions Pittsburgh Steelers15 - 30FINALMiami Dolphins Cincinnati Bengals17 - 35FINALNew England Patriots Carolina Panthers38 - 41FINALNew Orleans Saints Baltimore Ravens23 - 27FINALNew York Giants Cleveland Browns26 - 28FINALTennessee Titans Philadelphia Eagles20 - 27FINALWashington Commanders Kansas City Chiefs26 - 10FINALOakland Raiders Dallas Cowboys30 - 16FINALGreen Bay Packers Atlanta Falcons24 - 26FINALSeattle Seahawks Indianapolis Colts23 - 26FINALHouston Texans Mon, Oct 17
New York Jets3 - 28FINALArizona Cardinals
Box score is not available for this game