At a glance
All gamesHead-to-head6 recent
349ers wins
3Bills wins
Dec 7, 2020 · Week 13
Buffalo Bills34 - 24FINALSan Francisco 49ers Oct 16, 2016 · Week 6
San Francisco 49ers16 - 45FINALBuffalo Bills Oct 7, 2012 · Week 5
Buffalo Bills3 - 45FINALSan Francisco 49ers Nov 30, 2008 · Week 13
San Francisco 49ers10 - 3FINALBuffalo Bills Dec 26, 2004 · Week 16
Buffalo Bills41 - 7FINALSan Francisco 49ers Dec 2, 2001 · Week 12
Buffalo Bills0 - 35FINALSan Francisco 49ers
FormLast five before this game
49ersLWWLL
San Francisco 49ers10 - 38FINALGreen Bay PackersSeattle Seahawks20 - 17FINALSan Francisco 49ersSan Francisco 49ers23 - 20FINALTampa Bay BuccaneersDallas Cowboys24 - 30FINALSan Francisco 49ersKansas City Chiefs28 - 18FINALSan Francisco 49ers BillsWWWWW
Kansas City Chiefs21 - 30FINALBuffalo BillsBuffalo Bills30 - 20FINALIndianapolis ColtsMiami Dolphins27 - 30FINALBuffalo BillsBuffalo Bills31 - 10FINALSeattle SeahawksTennessee Titans10 - 34FINALBuffalo Bills
Also in Week 132024 season
Thu, Nov 28
Chicago Bears20 - 23FINALDetroit Lions New York Giants20 - 27FINALDallas Cowboys Miami Dolphins17 - 30FINALGreen Bay Packers Fri, Nov 29
Las Vegas Raiders17 - 19FINALKansas City Chiefs Sun, Dec 1
Los Angeles Chargers17 - 13FINALAtlanta Falcons Pittsburgh Steelers44 - 38FINALCincinnati Bengals Houston Texans23 - 20FINALJacksonville Jaguars Arizona Cardinals22 - 23FINALMinnesota Vikings Indianapolis Colts25 - 24FINALNew England Patriots Seattle Seahawks26 - 21FINALNew York Jets Tennessee Titans19 - 42FINALWashington Commanders Tampa Bay Buccaneers26 - 23FINALCarolina Panthers Los Angeles Rams21 - 14FINALNew Orleans Saints Philadelphia Eagles24 - 19FINALBaltimore Ravens Mon, Dec 2
Cleveland Browns32 - 41FINALDenver Broncos
Box score is not available for this game