By surface
| Surface | Daniil Medvedev | John Isner |
|---|---|---|
| Hard | 2 | 0 |
All meetings (2)
| Date | Tour | Tournament | Round | Surface | Winner | Set 1 | Set 2 | Set 3 | Set 4 | Set 5 |
|---|---|---|---|---|---|---|---|---|---|---|
| 2021-08-09 | ATP | Canada Masters | Semifinal | Hard | Daniil Medvedev | 6-2 | 6-2 | |||
| 2020-01-06 | ATP | ATP Cup | Round Robin | Hard | Daniil Medvedev | 6-3 | 6-1 |