By surface
| Surface | Reilly Opelka | Denis Istomin |
|---|---|---|
| Hard | 2 | 0 |
All meetings (2)
| Date | Tour | Tournament | Round | Surface | Winner | Set 1 | Set 2 | Set 3 | Set 4 | Set 5 |
|---|---|---|---|---|---|---|---|---|---|---|
| 2020-03-06 | ATP | Davis Cup QLS R1: USA vs UZB | Round Robin | Hard | Reilly Opelka | 6-2 | 7-5 | |||
| 2019-02-11 | ATP | New York | Round of 16 | Hard | Reilly Opelka | 6-78 | 7-66 | 1-0 |